These results revealed that methanolic extracts of abelmoschus esculentus have better antioxidant and antidiabetic activity than ethanol and aqueous extracts which support the medicinal properties. The antidiabetic activity of nigella sativa and propolis. Abelmoschus moschatus medik malvaceae whole plant contains myricelin which enhances insulin sensitivity through increasing postreceptor transduction in muscle. Evaluation of antidiabetic activity of euphorbia hirta linn. The potent antidiabetic effect of the plant extract suggests the presence of potent antidiabetic active principles, which produced antihyperglycemic effect in diabetic rats 15,19. Doses which have antidiabetic activity were reported as 50 and 100 mgkg body weight. Kuntze ethanolic extracts in streptozotocinnicotinamide induced diabetic rats. Acute toxicity of aepp and aesp was studied in rats at 2000 mgkg dose and diabetes was induced in rats by administration of stz 60 mgkg, i. Approach to phytochemistry and mechaniasm of action of plants having antidiabetic activity. Antidiabetic activity of medicinal plants and its relationship with their antioxidant property.
Emblica officinalis, their combination triphala for their antidiabetic activity and their relation with. Myricetin might be used as a model substance for the development of antidiabetic compounds 5. The mechanism of action of myricetin seems to be the. Comparison with the antiviral activity of propolis. Antidiabetic activity of the compounds isolated from. The musk mallow abelmoschus moschatus improves insulin resistance. The aim was to evaluate the antiurolithiatic activity of abelmoschus.
Artemis sphaerocephala krasch 12 antioxidant effect of artemis sphaerocephala a. The monech seeds of abelmoschus esculentus having potential in the development of a drug for diabetes due to their antidiabetic activity. Okolo rural dwellers in nigeria often resort to herbal remedy and dietary control in the treatment of diabetes mellitus dm. Shamim hossain, naim hassan, biplab kumar dash, md. This species is regarded as a weed outside its natural habitats. The aim was to evaluate the antiurolithiatic activity of abelmoschus moschatus seed extracts in rats. Though different types of oral hypoglycemic agents are available along with insulin for the treatment of diabetes mellitus. Antidiabetic activity of abelmoschus esculentus fruit extract. Myricetin as the active principle of abelmoschus moschatus to lower. The hypoglycemic activity of myricetin has been investigated in streptozotocininduced diabetic rats 94 using an i. The main objective of this work is to evaluate the in vitro anti diabetic activity of methanolic. Abelmoschus moschatus is an aromatic medicinal plant commonly found in bangladesh and nearly india. Antiurolithiatic activity of abelmoschus moschatus seed.
The commonly used techniques for removing renal calculi are associated with the risk of acute renal injury and increase in stone recurrence which indicates an urgent need for alternate therapy. Home pharmacogn j, vol 10, issue 1, janfeb, 2018 antidiabetic activity studies of white tea camellia sinensis l. The hypoglycemic activity of this plants extract was tested by using. On administration of graded doses of berberine to normal and. Evaluation of in vitro anti diabetic activity of selected plant extracts sindhu. Myricetin as the active principle of abelmoschus moschatus to lower plasma glucose in. Ashrafuzzaman sapon, monokesh kumer sen abstract in the last few years, there has been an exponential growth in the field of herbal medicine and gaining. Evaluation of antidiabetic activity of abelmoschus esculentus extracts body weight and blood glucose levels of rats were studied to determine the effectiveness of abelmoschus esculentus extracts. Antidiabetic activity of alcohol of celosia argentea linn. In vitro antidiabetic activity of cardiospermum halicacabum leaves extracts by stalin. The obtained data were comparable with gliclazide, a standard reference drug for diabetes. The ethanolic extracts and the hexane and chloroform fractions of leaves and fruit peels showed promising antidiabetic activity in stzs model.
Evaluation of hepatoprotective activity of abelmoschus. The following medicinal plants products or extracts showed promising effects as enzyme inhibitors. Myricetin is a phenolic compound isolated from the aerial part of abelmoschus moschatus malvaceae. Research article open access evaluation of abelmoschus. Effect of boiling and roasting on the antidiabetic. The present study was carried out to evaluate the antidiabetic activity of vinca rosea methanolic whole plant extracts in alloxan induced diabetic rats for 14 days. Hypoglycemic activity due to increase in the peripheral metabolism of glucose was seen in some plants and these experiments were carried out on rabbits with experimentally induced diabetes 23.
Pdf antidiabetic activity of abelmoschus esculentus ex. The leaves of bauhinia purpurea orchid tree were found to possess, in addition to antidiabetic activity, antioxidant and antihyperlipidemic activities 24. Chaenomeles sinensis is belongs to family rosaceae. It improves insulin sensitivity through increased postreceptor insulin signaling mediated by enhancements in irs1associated pi3kinase and glut 4 activity in muscles of obese zucker rats 23. Research article open access evaluation of abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays mir z gul1, lepakshi m bhakshu1, farhan ahmad2, anand k kondapi2, insaf a qureshi2 and irfan a ghazi1 abstract. The hypoglycemic activity of myricetin isolated from. Nutritional quality and health benefits of okra abelmoschus esculentus. Abelmoschus esculentus, okra, diabetes mellitus, diabetic nephropathy. Pdf evaluation of abelmoschus moschatus extracts for antioxidant. Evaluation of in vitro anti diabetic activity of selected. Antidiabetic activity of the compounds isolated from rhus mysorensis plant extract doi. The most useful medicinal herbs to treat diabetes biomedical. A rewiew on antidiabetic angiospermic plants from the.
Jcprc5 269 protective effect of methanolic extract of abelmoschus moschatus seeds against calcium oxalate urolithiasis in rats a. Antiurolithiatic activity of abelmoschus moschatus seed extracts against zinc disc implantationinduced urolithiasis in rats abstract background. This effort is seen towards providing the evidence support to motivate more scientific research to uncover more scientific nutritional properties of abelmoschus esculentus that may be benefited by the modern medicine, thus suggesting new potential target for drug discovery. Evaluation of antidiabetic activity of isolated compound. Approach to phytochemistry and mechaniasm of action of. Candida albicans were used to evaluate its antimicrobial activity. Diabetes mellitus is a complex metabolic disorder that affects between 6 to 20% of the population in western industrialized societies, with an estimated worldwide prevalence of 150 million people in 2000, a number that is expected to increase to 220. The effect of boiling and roasting on the antidiabetic activity of abelmoschus esculentus okra fruits and seeds in type 2 diabetic rats was. Department of medicinal chemistry and pharmacognosy, college of pharmacy, university of illinois at. The results from this study showed that the antioxidant activities of a.
Myricetin an isolated compound from abelmoschus moschatus showed ic 50 of 0. Abelmoschus esculentus as remedy to manage diabetes. It has repeatedly escaped from cultivation to become naturalized, primarily in cultivated, ruderal and seminatural areas. Aromatic and medicinal plants with antidiabetic potential. Enzymes inhibitors from natural sources with antidiabetic.
Improvement of insulin sensitivity in obese zucker rats by myricetin extracted from abelmoschus moschatus. Abelmoschus moschatus, alangium salvifolium, azadirachta indica, bidens pilosa, boerhaavia diffusa, capsicum frutescens. Animal models to test drugs with potential antidiabetic activity t. Antiurolithiatic activity of abelmoschus moschatus seed extracts against zinc disc implantationinduced urolithiasis in rats. Abelmoschus moschatus is an aromatic and medicinal plant that has been widely introduced across tropical, subtropical and temperate regions of the world. The present study was designed to investigate the glucose uptake of antidiabetic activity crude nhexane,ethanol, methanol and aqueous leaf. Abelmoschus esculentus are having potential in the.
Malvaceae is described in medicine for the treatment of diabetes mellitus. Woldegiorgis abstract okra abelmoschus esculentus is an economically important vegetable crop grown in tropical and subtropical parts of the world. A rewiew on antidiabetic angiospermic plants from the regions of uttarakhand, india 16 s r. Antiurolithiatic activity of abelmoschus moschatus seed extracts. Ethnomedicinal, phytochemical and pharmacological profile of. Antidiabetic activity studies of white tea camellia.
Evaluation of hepatoprotective activity of abelmoschus moschatus seed in paracetamol induced 44 animals. This study was conducted to compare the ameliorative effect of nigella sativa and propolis methanol extract on streptozotocininduced diabetic male rats and treating diabetic nephropathy. Forty male albino rats were divided into four groups. Antidiabetic activity of vinca rosea extracts in alloxan. Antioxidant and antidiabetic properties of abelmoschus. Abelmoschus is a genus of about fifteen species of flowering plants in. Preeti sen, kamlesh sahu, pushpa prasad, shashikant chandrakar, ram kumar sahu, amit roy. The present investigation aimed to study the effect of two culinary treatments boiling and roasting on the antidiabetic potential of abelmoschus esculentus fruits and seeds in type 2 diabetic rats. Antidiabetic potential of purple okra abelmoschus esculentus l.
Antidiabetic activity of the aqueous extracts of foeniculum vulgare on streptozotocininduced diabetic rats t anitha1, 2c balakumar,k b ilango 3, c benedict jose,d vetrivel3. Ethnomedicinal, phytochemical and pharmacological profile of genus abelmoschus onakpa m. Panax, cinnamomum verum, abelmoschus moschatus, vachellia nilotica, achyranthes, fabaceae. Evaluation of antidiabetic activity of euphorbia hirta. The methanolic whole plant extract at high dose 500 mgkg exhibited significant antihyperglycemic activity than whole plant extract at low dose 300 mgkg in diabetic rats. M department of veterinary physiology and biochemistry, faculty of veterinary medicine, university of abuja, pmb 117, abuja, nigeria. Shows comparison of mean blood glucose levels between normal control, diabetic control, standard and test groups in aqueous extract treated rats. The hypoglycemic effect of the extract was tested in normal, glucose loading and alloxaninduced diabetic rats. Complementary and alternative medicine for type 2 diabetes. Nair1, vaibhavi kavrekar1, anshu mishra1 1 department of biotechnology, mount carmel college, bangalore, karnataka, india abstract. P abelmoschus moschatus malvaceae chemical part all parts. Antidiabetic phytoconstituents and their mode of action on.
The aromatic seeds of this plant are aphrodisiac, ophthalmic, cardio tonic, antispasmodic and used in the treatment of intestinal complaints and check queasiness. Punica granatum, satureja khuzestanica and bauhinia forficate. List of all chemicals abelmoschus moschatus malvaceae. Type 2 dm, which accounts for over 90% of the cases, is associated with disordered. There was a sudden increase in body weight on 28th day of the study with the. Original article experimental evaluation of antidiabetic. Serum glucose levels and activities of enzymes viz. Petroleum ether and ethyl acetate fractions of the leaves of coccinia cordifolia have potential antidiabetic activity 6061. Abelmoschus esculentus linn, antidiabetic activity, oral glucose tolerance test, aqueous and ethanolic extracts, insulin, introduction diabetes mellitus is a metabolic disorder characterized by hyperglycemia and alterations in carbohydrate, fat and protein metabolism, associated with absolute or. Ethnomedicinal, phytochemical and pharmacological profile. Bidens pilosa referred as black jack is a perennial flowering plant belonging to family asteraceae.
Antidiabetic activity of abelmoschus esculentus ex maradi okra fruit in alloxaninduced diabetic rats article pdf available march 2018 with 1,529 reads how we measure reads. Crude fiber, total phenolic content, and in vitro free radical scavenging capacity of the various culinary forms of the fruits and seeds were assessed. Myricelin is the primary active constituents of this plant, which improves insulin sensitivity through increased post receptor insulin signaling mediated by enhancements in irs1associated pi3kinase and glut 4 activity in muscles of obese. The present investigation was aimed to study the antidiabetic and antihyperlipidemic potential of abelmoschus esculentus peel and seed powder aepp and aesp in streptozotocin stzinduced diabetic rats. The outcomes of lipid profile confirmed the potent antidiabetic activity of bark and root of o. Antidiabetic activity of aqueous and methanol extract and fractions of gongronema latifolium leaves in alloxan diabetic rats p. Hence, it was concluded that gossypin has potent antidiabetic activity in streptozotocininduced experimental diabetes in rats.
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